Integratore di vitamina C

[giuseppesole]

Notavo che, per quanto riguarda i prodotti Universal, la Vit C Formula (più economica) è acido ascorbico, mentre la Buffered Vitamin C, più pregevole e solitamente preferita, è ascorbato di calcio.... forse proprio per renderne l' assunzione graduale (non a caso si presenta in dosaggi da 1g).

E cito testualmente: "Buffered Vitamin C has twice the potency of our regular Vitamin C Formula at 1000mg."

[AndryPata90]

oat secondo la tua conoscenza che ne pensi in merito?

[mr oat]

Does vitamin C and E supplementation impair the favorable adaptations of regular exercise?
Nikolaidis MG, Kerksick CM, Lamprecht M, McAnulty SR.
Source
Department of Physical Education and Sports Science at Serres, Aristotle University of Thessaloniki, Serres, Greece. nikolaidis@auth.gr
Abstract
The detrimental outcomes associated with unregulated and excessive production of free radicals remains a physiological concern that has implications to health, medicine and performance. Available evidence suggests that physiological adaptations to exercise training can enhance the body's ability to quench free radicals and circumstantial evidence exists to suggest that key vitamins and nutrients may provide additional support to mitigate the untoward effects associated with increased free radical production. However, controversy has risen regarding the potential outcomes associated with vitamins C and E, two popular antioxidant nutrients. Recent evidence has been put forth suggesting that exogenous administration of these antioxidants may be harmful to performance making interpretations regarding the efficacy of antioxidants challenging. The available studies that employed both animal and human models provided conflicting outcomes regarding the efficacy of vitamin C and E supplementation, at least partly due to methodological differences in assessing oxidative stress and training adaptations. Based on the contradictory evidence regarding the effects of higher intakes of vitamin C and/or E on exercise performance and redox homeostasis, a permanent intake of non-physiological dosages of vitamin C and/or E cannot be recommended to healthy, exercising individuals.


altro studio

Effect of vitamin C supplements on physical performance.


Braakhuis AJ.
Source
US Olympic Committee, Sport Performance, Olympic Training Center, Chula Vista, CA 91915, USA. andrea.braakhuis@usoc.org
Abstract
Vitamin C is an essential component of the diet and may reduce the adverse effects of exercise-induced reactive oxygen species, including muscle damage, immune dysfunction, and fatigue. However, reactive oxygen species may mediate beneficial training adaptations that vitamin C attenuates; indeed, from a total of 12 studies, vitamin C in doses >1 g·d(-1) impaired sport performance substantially in four of four studies, possibly by reducing mitochondrial biogenesis, while a further four studies demonstrated impairments that were not statistically significant. Doses of ∼0.2 g·d(-1) of vitamin C consumed through five or more servings of fruit and vegetables may be sufficient to reduce oxidative stress and provide other health benefits without impairing training adaptations.


3 studio



Vitamin C status and perception of effort during exercise in obese adults adhering to a calorie-reduced diet.
Huck CJ, Johnston CS, Beezhold BL, Swan PD.
Source
Department of Health Promotion and Human Development, University of Wisconsin, Stevens Point, Wisconsin, USA.
Abstract
OBJECTIVE:
Moderate energy restriction and exercise are recommended for effective weight loss. Obese individuals oxidize less fat and report a higher perceived exertion during exercise, characteristics that may negatively influence exercise behavior. Because vitamin C status has been linked to fatigability, we compared the effects of vitamin C supplementation on self-reported fatigue and on the respiratory exchange ratio and the Ratings of Perceived Exertion scale during moderate exercise in healthy obese adults adhering to a hypocaloric diet.
METHODS:
Twenty adults (4 men and 16 women) were stratified and randomly assigned to receive 500 mg of vitamin C (VC) or placebo (CON) daily for 4 wk while adhering to a vitamin C-controlled, calorie-restricted diet. Feelings of general fatigue as assessed by the Profile of Mood States questionnaire were recorded on a separate day from the exercise session at weeks 0 and 4. Participants walked on a treadmill at an intensity of 50% predicted maximal oxygen consumption for 60 min at weeks 0 and 4, and heart rate, respiratory exchange ratio, and Ratings of Perceived Exertion were recorded.
RESULTS:
After 4 wk, the two groups lost similar amounts of weight (≈ 4 kg), and the respiratory exchange ratio was not altered by group. Heart rate and the Ratings of Perceived Exertion during exercise were significantly decreased in the VC versus the CON group (-11 versus -3 beats/min, P = 0.022, and -1.3 versus +0.1 U, P = 0.001, respectively), and the general fatigue score was decreased 5.9 U for the VC group versus a 1.9 U increase for the CON group (P = 0.001).
CONCLUSION:
These data provide preliminary evidence that vitamin C status may influence fatigue, heart rate, and perceptions of exertion during moderate exercise in obese individuals.





Vitamin C infusion treatment enhances cortisol production of the adrenal via the pituitary ACTH route.



Kodama M, Kodama T, Murakami M, Kodama M.
Source
Kodama Research Institute of Preventive Medicine, Nagoya, Japan.
Abstract
The present study is an extension of our past study on the clinical use of vitamin C infusion or injection treatment in autoimmune disease and allergy which suggests that the intravenous introduction of vitamin C may enhance the activity of the endogenous cortisol in such a way as to allow clinical control of immune disorders. This time, we investigated the relation between ACTH, cortisol and vitamin C in plasma in the course of vitamin C infusion or injection treatment with and without the use of methyl-prednisolone annex, a suppressor of the homeostatic mechanism of the pituitary ACTH. A total of 4 experiments were conducted using a healthy male volunteer. Results obtained are as follows: 1) the practice of the steroid-free vitamin C infusion treatment induced a) distinct depletion of both cortisol and vitamin C from the circulation at the initial to moderate stages of the experiment, b) a small surge of plasma cortisol at the middle stage, and c) skyrocket-like rises of ACTH and cortisol of plasma at the terminal stage. 2) The use of methylprednisolone annex in the vitamin C infusion set completely suppressed the emergence of the plasma ACTH/cortisol surges of the terminal stage, but not the small surge of plasma cortisol. The synthetic steroid also suppressed the depletion of vitamin C and cortisol of the initial to moderate stages. 3) The terminal ACTH/cortisol surges of plasma were less distinct in the vitamin C infection experiment than in the vitamin C infusion experiment.(ABSTRACT TRUNCATED AT 250 WORDS)

[mr oat]

oat secondo la tua conoscenza che ne pensi in merito?

io assumo 4 gr al giorno di vit C da piu di 4 anni in capsule da 1gr in ogni pasto e ho avuto notevoli benefici, sulla salute ma principalmente sulla vascolarizzazione e minor stanchezza dovuta allo stress ossidativo... su di me funziona al 100% e non ne posso fare a meno.. riguardo l'assunzione postwo la valuto una scelta sbagliata per la funzione anti infiammatoria

[giuseppesole]

Oat, e tu fai differenza tra acido ascorbico ed ascorbati?

[elan]

concordo sul postW,come il non assumere omega3 a ridosso del workout ma imo stiamo parlando davvero di tecnicismi abbastanza esasperati

quando sn passato da un multi "normale"(medi dosaggi)ad uno strong(adam-orange triad su tutti)ho avuto un periodo di "adattamento"e credo di aver buttato il 50-60% delle idrosolubili nel water per piu di 1 mese.credo che le dosi di vitaminaC(sia come assunzione che come assorbimento)siano molto soggettive...far adattare il corpo non partendo da megadosi imo è la soluzione migliore

se si assume da anni 4gr die credo sia ovvio che le caps da 1gr siano ok

imo obv

[mr oat]

ovvio..infatti utilizzo solo ascorbati

[mr oat]

concordo sul postW,come il non assumere omega3 a ridosso del workout ma imo stiamo parlando davvero di tecnicismi abbastanza esasperati

quando sn passato da un multi "normale"(medi dosaggi)ad uno strong(adam-orange triad su tutti)ho avuto un periodo di "adattamento"e credo di aver buttato il 50-60% delle idrosolubili nel water per piu di 1 mese.credo che le dosi di vitaminaC(sia come assunzione che come assorbimento)siano molto soggettive...far adattare il corpo non partendo da megadosi imo è la soluzione migliore

se si assume da anni 4gr die credo sia ovvio che le caps da 1gr siano ok

imo obv

ok che non assumerla postwo puo essere un estremismo troppo tecnico, ma perche andare a peggiorare quel dato periodo di tempo quando hai tutta la giornata per assumerla?

[MD_CORPORATION]

assumi 4 gr ... ma scusa la mia ignoranza ma su cosa ti sei basato ? in quali momenti della giornata assumi ? dopo i pasti o anche a stomaco vuoto ? ogni assunzione è sempre di 1gr? hai iniziato subito con un gr per volta o "consigli di partire prima con dosaggi più leggeri?

scusa le troppe domande XD

[brosgym]

Un discorso é il passaggio a livello gastrico, sul quale può incidere l'assumere il sale (ascorbato) o l'acido (ascorbico), il passaggio al plasma dipende dalla quantità di un grammo é sicuro che metà finisca nel water.......unico modo sarebbe una forma retard, o in un pasto particolarmente abbondante.
Con il cortisolo, direttamente ha poco a che fare
Postwo dipende dal wo
Oltre i due grammi non andrei, sia per la reale efficacia che per le dosi che sarebbero troppe, e poicon tutti gli antiox che ci sono perché delegare tutto alla vitamina C?

[brosgym]

Un discorso é il passaggio a livello gastrico, sul quale può incidere l'assumere il sale (ascorbato) o l'acido (ascorbico), il passaggio al plasma dipende dalla quantità di un grammo é sicuro che metà finisca nel water.......unico modo sarebbe una forma retard, o in un pasto particolarmente abbondante.
Con il cortisolo, direttamente ha poco a che fare
Postwo dipende dal wo
Oltre i due grammi non andrei, sia per la reale efficacia che per le dosi che sarebbero troppe, e poicon tutti gli antiox che ci sono perché delegare tutto alla vitamina C?

[brosgym]

Does vitamin C and E supplementation impair the favorable adaptations of regular exercise?
Nikolaidis MG, Kerksick CM, Lamprecht M, McAnulty SR.
Source
Department of Physical Education and Sports Science at Serres, Aristotle University of Thessaloniki, Serres, Greece. nikolaidis@auth.gr
Abstract
The detrimental outcomes associated with unregulated and excessive production of free radicals remains a physiological concern that has implications to health, medicine and performance. Available evidence suggests that physiological adaptations to exercise training can enhance the body's ability to quench free radicals and circumstantial evidence exists to suggest that key vitamins and nutrients may provide additional support to mitigate the untoward effects associated with increased free radical production. However, controversy has risen regarding the potential outcomes associated with vitamins C and E, two popular antioxidant nutrients. Recent evidence has been put forth suggesting that exogenous administration of these antioxidants may be harmful to performance making interpretations regarding the efficacy of antioxidants challenging. The available studies that employed both animal and human models provided conflicting outcomes regarding the efficacy of vitamin C and E supplementation, at least partly due to methodological differences in assessing oxidative stress and training adaptations. Based on the contradictory evidence regarding the effects of higher intakes of vitamin C and/or E on exercise performance and redox homeostasis, a permanent intake of non-physiological dosages of vitamin C and/or E cannot be recommended to healthy, exercising individuals.


altro studio

Effect of vitamin C supplements on physical performance.


Braakhuis AJ.
Source
US Olympic Committee, Sport Performance, Olympic Training Center, Chula Vista, CA 91915, USA. andrea.braakhuis@usoc.org
Abstract
Vitamin C is an essential component of the diet and may reduce the adverse effects of exercise-induced reactive oxygen species, including muscle damage, immune dysfunction, and fatigue. However, reactive oxygen species may mediate beneficial training adaptations that vitamin C attenuates; indeed, from a total of 12 studies, vitamin C in doses >1 g·d(-1) impaired sport performance substantially in four of four studies, possibly by reducing mitochondrial biogenesis, while a further four studies demonstrated impairments that were not statistically significant. Doses of ∼0.2 g·d(-1) of vitamin C consumed through five or more servings of fruit and vegetables may be sufficient to reduce oxidative stress and provide other health benefits without impairing training adaptations.


3 studio



Vitamin C status and perception of effort during exercise in obese adults adhering to a calorie-reduced diet.
Huck CJ, Johnston CS, Beezhold BL, Swan PD.
Source
Department of Health Promotion and Human Development, University of Wisconsin, Stevens Point, Wisconsin, USA.
Abstract
OBJECTIVE:
Moderate energy restriction and exercise are recommended for effective weight loss. Obese individuals oxidize less fat and report a higher perceived exertion during exercise, characteristics that may negatively influence exercise behavior. Because vitamin C status has been linked to fatigability, we compared the effects of vitamin C supplementation on self-reported fatigue and on the respiratory exchange ratio and the Ratings of Perceived Exertion scale during moderate exercise in healthy obese adults adhering to a hypocaloric diet.
METHODS:
Twenty adults (4 men and 16 women) were stratified and randomly assigned to receive 500 mg of vitamin C (VC) or placebo (CON) daily for 4 wk while adhering to a vitamin C-controlled, calorie-restricted diet. Feelings of general fatigue as assessed by the Profile of Mood States questionnaire were recorded on a separate day from the exercise session at weeks 0 and 4. Participants walked on a treadmill at an intensity of 50% predicted maximal oxygen consumption for 60 min at weeks 0 and 4, and heart rate, respiratory exchange ratio, and Ratings of Perceived Exertion were recorded.
RESULTS:
After 4 wk, the two groups lost similar amounts of weight (≈ 4 kg), and the respiratory exchange ratio was not altered by group. Heart rate and the Ratings of Perceived Exertion during exercise were significantly decreased in the VC versus the CON group (-11 versus -3 beats/min, P = 0.022, and -1.3 versus +0.1 U, P = 0.001, respectively), and the general fatigue score was decreased 5.9 U for the VC group versus a 1.9 U increase for the CON group (P = 0.001).
CONCLUSION:
These data provide preliminary evidence that vitamin C status may influence fatigue, heart rate, and perceptions of exertion during moderate exercise in obese individuals.





Vitamin C infusion treatment enhances cortisol production of the adrenal via the pituitary ACTH route.



Kodama M, Kodama T, Murakami M, Kodama M.
Source
Kodama Research Institute of Preventive Medicine, Nagoya, Japan.
Abstract
The present study is an extension of our past study on the clinical use of vitamin C infusion or injection treatment in autoimmune disease and allergy which suggests that the intravenous introduction of vitamin C may enhance the activity of the endogenous cortisol in such a way as to allow clinical control of immune disorders. This time, we investigated the relation between ACTH, cortisol and vitamin C in plasma in the course of vitamin C infusion or injection treatment with and without the use of methyl-prednisolone annex, a suppressor of the homeostatic mechanism of the pituitary ACTH. A total of 4 experiments were conducted using a healthy male volunteer. Results obtained are as follows: 1) the practice of the steroid-free vitamin C infusion treatment induced a) distinct depletion of both cortisol and vitamin C from the circulation at the initial to moderate stages of the experiment, b) a small surge of plasma cortisol at the middle stage, and c) skyrocket-like rises of ACTH and cortisol of plasma at the terminal stage. 2) The use of methylprednisolone annex in the vitamin C infusion set completely suppressed the emergence of the plasma ACTH/cortisol surges of the terminal stage, but not the small surge of plasma cortisol. The synthetic steroid also suppressed the depletion of vitamin C and cortisol of the initial to moderate stages. 3) The terminal ACTH/cortisol surges of plasma were less distinct in the vitamin C infection experiment than in the vitamin C infusion experiment.(ABSTRACT TRUNCATED AT 250 WORDS)

I dosaggi citati non superano il grammo....

[mr oat]

Un discorso é il passaggio a livello gastrico, sul quale può incidere l'assumere il sale (ascorbato) o l'acido (ascorbico), il passaggio al plasma dipende dalla quantità di un grammo é sicuro che metà finisca nel water.......unico modo sarebbe una forma retard, o in un pasto particolarmente abbondante.
Con il cortisolo, direttamente ha poco a che fare
Postwo dipende dal wo
Oltre i due grammi non andrei, sia per la reale efficacia che per le dosi che sarebbero troppe, e poicon tutti gli antiox che ci sono perché delegare tutto alla vitamina C?

sono daccordo con tutto quello che hai detto...infatti il mio dosaggio e' da broscienza ma nella norma non consiglierei 3-4gr

[mr oat]

I dosaggi citati non superano il grammo....

si infatti...anzi rispecchia quello che dici tu...attenzione ripeto io non sto consigliando 3-4 gr, ma sto dicendo che bisogna mettere dei studi che supportino della affermazioni fatte in precedenza (non tue doc )

[feiwong]

io assumo 4 gr al giorno di vit C da piu di 4 anni in capsule da 1gr in ogni pasto e ho avuto notevoli benefici, sulla salute ma principalmente sulla vascolarizzazione e minor stanchezza dovuta allo stress ossidativo... su di me funziona al 100% e non ne posso fare a meno.. riguardo l'assunzione postwo la valuto una scelta sbagliata per la funzione anti infiammatoria

Ma allora anche tu vai a sensazioni Oat mi sa allora che di 4gr ne assimili meno della metà
Comunque io direi di non dare certi dogmi sull'integrazione ( visto l'alto rischio di emulazione). Non tutti sono avanzati o fanno alllenamenti massacranti da dover integrare in tal modo (sprecato per giunta). Io che mi alleno forte da più di 2 decenni e ho 45 anni trovo benefici con "appena" 2gr al giorno di vit C. Non sempre il di più è meglio. Inoltre come post wo intendo il pasto che è solitamente dopo 2 ore dall'allenamento e quasi 4 dalla assunzione di quella pre wo, quindi quale scelta sbagliata. Gli estremismi personali manteniamoli nei diari. Chiuso OT.