Fermenti probiotici: l'integratore sottovalutato

[Eagle]

Appena ho due minuti...posto quanto scritto dal Dott. Fabrizio Duranti sui fermenti probiotici.

Ci sono molti utori che scrivono moltissime cose, bellissime ed affascinanti.

E' uno dei problemi emergenti nella letteratura scientifica: ci sono un numero enorme e rapidamente crescente di documenti, ed e' difficile, se non se ne hanno le possibilita', capire cosa e' "significativo" e cosa no.

Se il dr Duranti scrive supportando quanto scrive con riferimenti a studi sensati, lo leggero' volentieri. Se invece si tratta delle purtroppo solite pagine e pagine di brainstorming in cui si elencano numerosissime proprieta' e concetti senza fornire alcun modo di verificarne la fondatezza, sara' un lettura assolutamente inutile.

Eagle

[odisseo]

nemmeno in caso di dissenteria è opprtuno integrarli?

[Eagle]

nemmeno in caso di dissenteria è opprtuno integrarli?

Nei bambini forse si, ma non ci sono ancora evidenze significative della cosa.

Quello sotto e' una review, dal database dell'associazione Cochrane, che e' una delle piu' importanti per la "analisi" di quanto i lavori scientifici sono significativi. come puoi leggere le conclusioni sono decisamente incerte.

A cosa poi possano servire nel giovane sano che pratica bb non penso proprio che lo abbia studiato nessuno.


Cochrane Database Syst Rev. 2007 Apr 18;(2):CD004827. Links

Probiotics for the prevention of pediatric antibiotic-associated diarrhea.

Johnston BC, Supina AL, Ospina M, Vohra S.
BACKGROUND: Antibiotics alter the microbial balance within the gastrointestinal tract. Probiotics may prevent antibiotic-associated diarrhea (AAD) via restoration of the gut microflora. Antibiotics are prescribed frequently in children and AAD is common in this population. OBJECTIVES: To assess the efficacy and adverse effects of probiotics (any specified strain or dose) for the prevention of antibiotic-associated diarrhea in children.To assess adverse events associated with the use of probiotics when co-administered with antibiotics in children. SEARCH STRATEGY: MEDLINE, EMBASE, CENTRAL, CINAHL , AMED, and the Web of Science (inception to August 2006) were searched along with specialized registers including the Cochrane IBD/FBD Review Group, CISCOM, Chalmers PedCAM Research Register and trial registries from inception to 2005. Letters were sent to authors of included trials, nutra/pharmaceutical companies, and experts in the field requesting additional information on ongoing or unpublished trials. Conference proceedings, dissertation abstracts, and reference lists from included and relevant articles were hand searched. SELECTION CRITERIA: Randomized, parallel, controlled (placebo, active, or no treatment) trials comparing co-administered probiotics with antibiotics for the prevention of diarrhea secondary to antibiotic use in children (0 to 18 years). DATA COLLECTION AND ANALYSIS: Methodological quality assessment and data extraction were conducted independently by two authors (BCJ, AS). Dichotomous data (incidence of diarrhea, adverse events) were combined using pooled relative risks, and continuous data (mean duration of diarrhea, mean daily stool frequency) as weighted mean differences, along with their corresponding 95% confidence intervals. Adverse events were summarized using risk difference. For overall pooled results on the incidence of diarrhea, a priori sensitivity analyses included per protocol versus intention to treat, random versus fixed effects, and methodological quality criterion. Subgroup analysis were conducted on probiotic strain, dose, definition of antibiotic-associated diarrhea, and antibiotic agent. MAIN RESULTS: Ten studies met the inclusion criteria. Trials included treatment with either Lactobacilli spp., Bifidobacterium spp., Streptococcus spp., or Saccharomyces boulardii alone or in combination. Six studies used a single strain probiotic agent and four combined two probiotic strains.The per protocol analysis for 9/10 trials reporting on the incidence of diarrhea show statistically significant results favouring probiotics over active/non active controls (RR 0.49; 95% CI 0.32 to 0.74). However, intention to treat analysis showed non-significant results overall (RR 0.90; 95% CI 0.50 to 1.63). Five of ten trials monitored for adverse events (n = 647); none reported a serious adverse event. AUTHORS' CONCLUSIONS: Probiotics show promise for the prevention of pediatric AAD. While per protocol analysis yields treatment effect estimates that are both statistically and clinically significant, as does analysis of high quality studies, the estimate from the intention to treat analysis was not statistically significant. Future studies should involve probiotic strains and doses with the most promising evidence (e.g., Lactobacillus GG, Lactobacillus sporogenes, Saccharomyces boulardii at 5 to 40 billion colony forming units/day). Research done to date does not permit determination of the effect of age (e.g., infant versus older children) or antibiotic duration (e.g., 5 days versus 10 days). Future trials would benefit from a validated primary outcome measure for antibiotic-associated diarrhea that is sensitive to change and reflects what treatment effect clinicians, parents, and children consider important. The current data are promising, but it is premature to routinely recommend probiotics for the prevention of pediatric AAD.

[Hombrillo]

spesso è semplicemente disidratazione.
è che a sharm (eri a sharm vero?) si tende a dimenticare di essere in mezzo al deserto, l'organismo ha molto bisogno di liquidi.

la stragrande maggioranza dei mali da maledizione del faraone è disidratazione (per la prossima volta, bevi anche se non hai sete, bevi di continuo)

bevevo di continuo credimi la mia ragazza si porta sempre dietro la borsetta con dentro 2 bottiglie d'acqua

credo fosse semplicemente qlke alimento "pesante"

grazie cmq dell'intervento

[Eagle]

bevevo di continuo credimi la mia ragazza si porta sempre dietro la borsetta con dentro 2 bottiglie d'acqua

credo fosse semplicemente qlke alimento "pesante"

grazie cmq dell'intervento

scusa, si puo' sapere che sintomi avevi?

perche' non e' che la disidratazione si confonda con molte altre cose, e poi se uno e' nel deserto disidratato come minimo ha una sete immensa...

[DORIAN]

Nei bambini forse si, ma non ci sono ancora evidenze significative della cosa.

Quello sotto e' una review, dal database dell'associazione Cochrane, che e' una delle piu' importanti per la "analisi" di quanto i lavori scientifici sono significativi. come puoi leggere le conclusioni sono decisamente incerte.

A cosa poi possano servire nel giovane sano che pratica bb non penso proprio che lo abbia studiato nessuno.


Cochrane Database Syst Rev. 2007 Apr 18;(2):CD004827. Links

Probiotics for the prevention of pediatric antibiotic-associated diarrhea.

Johnston BC, Supina AL, Ospina M, Vohra S.
BACKGROUND: Antibiotics alter the microbial balance within the gastrointestinal tract. Probiotics may prevent antibiotic-associated diarrhea (AAD) via restoration of the gut microflora. Antibiotics are prescribed frequently in children and AAD is common in this population. OBJECTIVES: To assess the efficacy and adverse effects of probiotics (any specified strain or dose) for the prevention of antibiotic-associated diarrhea in children.To assess adverse events associated with the use of probiotics when co-administered with antibiotics in children. SEARCH STRATEGY: MEDLINE, EMBASE, CENTRAL, CINAHL , AMED, and the Web of Science (inception to August 2006) were searched along with specialized registers including the Cochrane IBD/FBD Review Group, CISCOM, Chalmers PedCAM Research Register and trial registries from inception to 2005. Letters were sent to authors of included trials, nutra/pharmaceutical companies, and experts in the field requesting additional information on ongoing or unpublished trials. Conference proceedings, dissertation abstracts, and reference lists from included and relevant articles were hand searched. SELECTION CRITERIA: Randomized, parallel, controlled (placebo, active, or no treatment) trials comparing co-administered probiotics with antibiotics for the prevention of diarrhea secondary to antibiotic use in children (0 to 18 years). DATA COLLECTION AND ANALYSIS: Methodological quality assessment and data extraction were conducted independently by two authors (BCJ, AS). Dichotomous data (incidence of diarrhea, adverse events) were combined using pooled relative risks, and continuous data (mean duration of diarrhea, mean daily stool frequency) as weighted mean differences, along with their corresponding 95% confidence intervals. Adverse events were summarized using risk difference. For overall pooled results on the incidence of diarrhea, a priori sensitivity analyses included per protocol versus intention to treat, random versus fixed effects, and methodological quality criterion. Subgroup analysis were conducted on probiotic strain, dose, definition of antibiotic-associated diarrhea, and antibiotic agent. MAIN RESULTS: Ten studies met the inclusion criteria. Trials included treatment with either Lactobacilli spp., Bifidobacterium spp., Streptococcus spp., or Saccharomyces boulardii alone or in combination. Six studies used a single strain probiotic agent and four combined two probiotic strains.The per protocol analysis for 9/10 trials reporting on the incidence of diarrhea show statistically significant results favouring probiotics over active/non active controls (RR 0.49; 95% CI 0.32 to 0.74). However, intention to treat analysis showed non-significant results overall (RR 0.90; 95% CI 0.50 to 1.63). Five of ten trials monitored for adverse events (n = 647); none reported a serious adverse event. AUTHORS' CONCLUSIONS: Probiotics show promise for the prevention of pediatric AAD. While per protocol analysis yields treatment effect estimates that are both statistically and clinically significant, as does analysis of high quality studies, the estimate from the intention to treat analysis was not statistically significant. Future studies should involve probiotic strains and doses with the most promising evidence (e.g., Lactobacillus GG, Lactobacillus sporogenes, Saccharomyces boulardii at 5 to 40 billion colony forming units/day). Research done to date does not permit determination of the effect of age (e.g., infant versus older children) or antibiotic duration (e.g., 5 days versus 10 days). Future trials would benefit from a validated primary outcome measure for antibiotic-associated diarrhea that is sensitive to change and reflects what treatment effect clinicians, parents, and children consider important. The current data are promising, but it is premature to routinely recommend probiotics for the prevention of pediatric AAD.

eagle gentilmente potresti esprimere il succo del testo e in italiano..
Molti nn sanno tradurre certi testi...te lo chiedo anche per eventuali altri interventi...sarebbe meglio per la maggiorparte degli utenti...grazie intanto in anticipo.

[Hulkhogan]

Io uso un prodotto della Pegaso e mi trovo benissimo. Con benissimo intendo che quando li prendo mi accorgo che riesco ad assimilare meglio quello che mangio, nel senso che vado meno frequentemente in bagno!!

[DORIAN]

Io uso un prodotto della Pegaso e mi trovo benissimo. Con benissimo intendo che quando li prendo mi accorgo che riesco ad assimilare meglio quello che mangio, nel senso che vado meno frequentemente in bagno!!

lo usi a cicli?che prodotto sarebbe?

[Hulkhogan]

lo usi a cicli?che prodotto sarebbe?

Il prodotto si chiama EnteroDophilus, ogni capsula possiede 10 miliardi di fermenti vivi e non contiene lattosio. Ha quindi il pregio di essere molto comodo e "dosabile" a seconda delle necessità. 40 cps costano 18 €.

Solitamente ne compro una confezione nei periodi che ho qualche fastidio intestinale e dopo qualche gg la situazione si normalizza.