Coenzima Q10

[gabryboy]

Cosa mi sapete dire su questo "prodotto" a cosa serve....?
Quali sono le metodologie di assunzione?

[Zio]

mhh ne sò poco

Riguardo ai "muscoli" sò che carenze di coenzima Q10 possono portare a delle miopatie e che sono in via di sperimentazione cure su deficenze di coenzima Q10 tramite manipolazioni genetiche su modelli animali.....
Poi ricordo che l'uso del coenz.Q10 aveva prodotto sui tessuti muscolari un aumento di fibre a contrazione veloce (poco utilenel bb)il CoQ10 ha infatti,pare un ruolo nel metabolismo cellulare ..ma nn mi ricordo con precisione

poi mi sembra che una somministrazione di coemnzima Q10 possa aiutare chi affetto da asma bronchiale...

Poi avevo letto uno studio che parlava di supplementazione di carnitina,taurina e coenzima Q10 per migliorare la funzionalità del ventricolo cardiaco sinistro e poi vabbè l'uso del coenzima q10 per tutte quelle malattie di tipo neurodegenerativo(artereosclerori ,Alzehimer......)

[arabafenice]

insomma non sai una fava

[Zio]

Originally posted by arabafenice
insomma non sai una fava

meglio il ruolo delle tagliaelle al ragù

[Guru]

E' un buon antiossidante con proprietà cardioprotettive.
A dosaggi elevati diventa tossico e compromette l'efficienza muscolare.

Bacchettata per Zio!
Ahi ahi ahi!!!!!!!
Le fibre a contrazione veloce, dette anche bianche o di tipo II, sono quelle maggiormente ipertrofizzabili e con + alto potenziale di contrazione, quindi le più utili nel bbing

Bye.

[Goldrake]

Morale della favola?Serve assumerlo o no....magari insieme a qualche oliva???

G O L D

[pt]

pt

il coenzima q10 o ubidecarenone ha un vasto campo di applicazione nei soggetti cardiopatici per migliorare l'ossigenazione..si coporta da carrier di trasporto per gli elettroni......è un antiossidante........ migliora la capacità di contrazione cardiaca in soggetti affetti da patologie al miocardio..........e tanti ricercatori ah fatto numerosi studi per vedere se la sostanza apportasse modifiche positive alle prestazioni aerobiche......andava in voga negli anni 90 unitamente alla carnitina con capacità di ossidazione maggiore a livello mitocondriale...ma a mio avviso il gioco non vale la candela in quanto oltre al costo del prodotto..........i benefici sono poco percettibili e valutabili minimamente a maggior ragione in un body builder........da escludere in programmazione e supplemetazione

[gabryboy]

...SI, HO LETTO ANCHE IO CHE PER QUANTO RIGUARDO GLI SPORT AEROBICI, IL Q10 POTREBBE DARE DEI BENEFICI A LIVELLO DI ENERGIA (TEORIA DISCORDANTE)....PER QUANTO RIGUARDA IL B.B. QUINDI NON CI SONO DEGLI EFFETTI POSITIVI SIGNIFICATIVI.....

STAVO PRENDENDO UN PRODOTTO CHIAMATO:

EUFORTYN F ---->Q10 + CREATINA ED ALTRO..

LO FINISCO E PENSO DI NON ASSUMERLO PIù,.....ANCHE PERCHE' 10 FLACONI COSTANO UN BOTTO CIRCA 15 EURI

[Zio]

Originally posted by Guru
E' un buon antiossidante con proprietà cardioprotettive.
A dosaggi elevati diventa tossico e compromette l'efficienza muscolare.

Bacchettata per Zio!
Ahi ahi ahi!!!!!!!
Le fibre a contrazione veloce, dette anche bianche o di tipo II, sono quelle maggiormente ipertrofizzabili e con + alto potenziale di contrazione, quindi le più utili nel bbing

Bye.

ecco lo sapevo---se nn tiro un bidone nn sono in me

[NaturalMan]

Originally posted by gabryboy
...SI, HO LETTO ANCHE IO CHE PER QUANTO RIGUARDO GLI SPORT AEROBICI, IL Q10 POTREBBE DARE DEI BENEFICI A LIVELLO DI ENERGIA (TEORIA DISCORDANTE)....PER QUANTO RIGUARDA IL B.B. QUINDI NON CI SONO DEGLI EFFETTI POSITIVI SIGNIFICATIVI.....

STAVO PRENDENDO UN PRODOTTO CHIAMATO:

EUFORTYN F ---->Q10 + CREATINA ED ALTRO..

LO FINISCO E PENSO DI NON ASSUMERLO PIù,.....ANCHE PERCHE' 10 FLACONI COSTANO UN BOTTO CIRCA 15 EURI

se mapipolato con altri prodotti potrebbe risultare interessante....bisogna partire dal concetto che non sempre una dose maggiore è utile e necessaria... si tratta di microelementi e pertanto nn sono necessari grossi carichi... dalle reference che ho letto lo trovo molto interessante nn miracoloso ma sicuramente interessante più di un tribulus ecdisterone.... in accoppiata con ALA e complesso vitaminico ACE potrebbe diventare una bomba aniossidante ed un fenomenale catalizzatore proenergetico

Bliznakov EG et al. Biochemical and clinical consequences of inhibiting coenzyme Q(10) biosynthesis by lipid-lowering HMG-CoA reductase inhibitors (statins): a critical overview. 1998. Adv Ther 15: 218-228.

Ferrara N et al. Protective role of chronic ubiquinone administration on acute cardiac oxidative stress. 1995. J Pharmacol Exp Ther 274: 858-865.

Folkers K et al. Biochemical rationale and myocardial tissue data on the effective therapy of cardiomyopathy with coenzyme Q10. 1985. Proc Natl Acad Sci USA 82: 901-904.

Folkers K et al. A one year bioavailability study of coenzyme Q10 with 3 months withdrawal period. 1994. Molec Aspects Med 15, Suppl: S281-285.

Hanaki Y et al. Coenzyme Q10 and coronary artery
disease. 1993. Clin Investig 71, Suppl: S112-S115.

Kamikawa T et al. Effects of coenzyme Q10 on exercise tolerance in chronic stable angina pectoris. 1985. Am J Cardiol 56: 247-251.

Langsjoen H et al. Usefulness of coenzyme Q10 in clinical cardiology: a long-term study. 1994. Molec Aspects Med 15, Suppl: S165-S175.

Langsjoen P et al. Treatment of essential hypertension with coenzyme Q10. 1994. Molec Aspects Med 15, Suppl: S265-S272.

Langsjoen PH et al. The aging heart: reversal of diastolic
dysfunction through the use of oral CoQ10 in the elderly. In Klatz RM et al. (eds), Anti-Aging Medical Therapeutics. Health Quest Publications, 1997. Pp. 113-120.

Satoh K et al. Lipophilic HMG-CoA reductase inhibitors increase myocardial stunning in dogs. 2000. J Cardiovasc Pharmacol 35: 256-62.

Schardt F et al. Effect of coenzyme Q10 on ischaemia-induced ST-segment depression: a double blind, placebo-controlled crossover study. In Folkers K et al. (eds), Biomedical and Clinical Aspects of Coenzyme Q, vol. 5.

Elsevier, 1986. Pp. 385-403.

Senni M et al. Use of echocardiography in the management of congestive heart failure in the community. 1999. J Am Coll Cardiol 33: 164-170.

Serra G et al. Evaluation of CoQ10 in patients with moderate heart failure and chronic stable effort angina. In Folkers K et al. (eds), Biomedical and Clinical Aspects of Coenzyme Q, vol. 6. Elsevier, 1991. Pp. 327-338.

Singh RB et al. Randomized, double-blind placebo-controlled trial of coenzyme Q10 in patients with acute myocardial infarction. 1998. Cardiovasc Drugs Ther 12: 347-353.

Singh RB et al. Effect of coenzyme Q10 on experimental atherosclerosis and chemical composition and quality of atheroma in rabbits. 2000. Atherosclerosis 148: 275-282.

Soja AM et al. Treatment of congestive heart failure with coenzyme Q10 illuminated by meta-analyses of clinical
trials. 1997. Molec Aspects Med. 18, Suppl: S159-S168.

Tresch DD. The clinical diagnosis of heart failure in older patients. 1997. J Am Geriatr Soc 45: 1128-1133.


Alleva R et al. The protective role of ubiquinol-10 against formation of lipid hydroperoxides in human seminal fluid. 1997. Molec Aspects Med 18, Suppl: S221-228.

Dlugosz A et al. The chemoprotective effect of coenzyme Q on lipids in the paint and lacquer industry workers. 1998. Intl J Occup Med Env Health 11: 153-163.

Ernster L et al. Biochemical, physiological and medical aspects of ubiquinone function. 1995. Biochim Biophys Acta 1271: 195-204.

Forsmark-Andree P et al. Evidence for a protective effect of endogenous ubiquinol against oxidative damage to mitochondrial protein and DNA during lipid peroxidation. 1994. Molec Aspects Med 15, Suppl: S73-S81.

Forsmark-Andree P et al. Lipid peroxidation and changes in the ubiquinone content and the respiratory chain enzymes of submitochondrial particles. 1997. Free Radic Biol Med 22: 391-400.

Halliwell B et al. Free radicals in biology and medicine, 3rd edn. Oxford, 1999.

Harman D. Aging: A theory based on free radical and radiation chemistry. 1956. J Gerontol 12: 298-300.

Harman D. The biological clock: the mitochondria? 1972.
J Am Geriatr Soc 20: 145-147.

Harman D. Extending functional life span. 1998. Exp Gerontol 33: 95-112.

Humphries KM et al. Inhibition of NADH-linked mitochondrial respiration by 4-hydroxy-2-nonenal. 1998. Biochemistry 37: 552-557.

Kontush A et al. Antioxidative activity of ubiquinol-10 at physiologic concentrations in human low density lipoprotein. 1995. Biochem Biophys Acta 1258: 177-187.

Lewin A et al. The effect of Coenzyme Q10 on sperm
motility and function. 1997. Molec Aspects Med 18, Suppl: S213-S219.

Miquel J et al. Mitochondrial role in cell aging. 1980. Exp Gerontol 15: 575-591.

Miquel J. An update on the oxygen stress-mitochondrial mutation theory of aging: genetic and evolutionary
implications. 1998. Exp Gerontol 33: 113-126.

Stocker R et al. Ubiquinol-10 protects human low density lipoprotein more efficiently against lipid peroxidation that does a-tocopherol. 1991. Proc Natl Acad Sci USA 88:
1646-1650.

Thomas S et al. Cosupplementation with coenzyme Q prevents the prooxidant effect of a-tocopherol and increases the resistance of LDL to transition metal-dependent
oxidation initiation. 1996. Arterioscler Thromb Vasc Biol 16:
687-696.

Thomas S et al. Inhibition of LDL oxidation by ubiquinol-10. A protective mechanism for coenzyme Q in atherolsclerosis? 1997. Molec Aspects Med 18, Suppl:
S85-S103.

Thomas S et al. Oxidation and antioxidation of human
low-density lipoprotein and plasma exposed to 3-morpholinosydnonimine and reagent peroxynitrite. 1998. Chem Res Toxicol 11: 484-494.



Byeeeeeeeeeeeeeeeee

[Guru]

Originally posted by NaturalMan
se mapipolato con altri prodotti potrebbe risultare interessante....bisogna partire dal concetto che non sempre una dose maggiore è utile e necessaria... si tratta di microelementi e pertanto nn sono necessari grossi carichi... dalle reference che ho letto lo trovo molto interessante nn miracoloso ma sicuramente interessante più di un tribulus ecdisterone.... in accoppiata con ALA e complesso vitaminico ACE potrebbe diventare una bomba aniossidante ed un fenomenale catalizzatore proenergetico

Bliznakov EG et al. Biochemical and clinical consequences of inhibiting coenzyme Q(10) biosynthesis by lipid-lowering HMG-CoA reductase inhibitors (statins): a critical overview. 1998. Adv Ther 15: 218-228.

Ferrara N et al. Protective role of chronic ubiquinone administration on acute cardiac oxidative stress. 1995. J Pharmacol Exp Ther 274: 858-865.

Folkers K et al. Biochemical rationale and myocardial tissue data on the effective therapy of cardiomyopathy with coenzyme Q10. 1985. Proc Natl Acad Sci USA 82: 901-904.

Folkers K et al. A one year bioavailability study of coenzyme Q10 with 3 months withdrawal period. 1994. Molec Aspects Med 15, Suppl: S281-285.

Hanaki Y et al. Coenzyme Q10 and coronary artery
disease. 1993. Clin Investig 71, Suppl: S112-S115.

Kamikawa T et al. Effects of coenzyme Q10 on exercise tolerance in chronic stable angina pectoris. 1985. Am J Cardiol 56: 247-251.

Langsjoen H et al. Usefulness of coenzyme Q10 in clinical cardiology: a long-term study. 1994. Molec Aspects Med 15, Suppl: S165-S175.

Langsjoen P et al. Treatment of essential hypertension with coenzyme Q10. 1994. Molec Aspects Med 15, Suppl: S265-S272.

Langsjoen PH et al. The aging heart: reversal of diastolic
dysfunction through the use of oral CoQ10 in the elderly. In Klatz RM et al. (eds), Anti-Aging Medical Therapeutics. Health Quest Publications, 1997. Pp. 113-120.

Satoh K et al. Lipophilic HMG-CoA reductase inhibitors increase myocardial stunning in dogs. 2000. J Cardiovasc Pharmacol 35: 256-62.

Schardt F et al. Effect of coenzyme Q10 on ischaemia-induced ST-segment depression: a double blind, placebo-controlled crossover study. In Folkers K et al. (eds), Biomedical and Clinical Aspects of Coenzyme Q, vol. 5.

Elsevier, 1986. Pp. 385-403.

Senni M et al. Use of echocardiography in the management of congestive heart failure in the community. 1999. J Am Coll Cardiol 33: 164-170.

Serra G et al. Evaluation of CoQ10 in patients with moderate heart failure and chronic stable effort angina. In Folkers K et al. (eds), Biomedical and Clinical Aspects of Coenzyme Q, vol. 6. Elsevier, 1991. Pp. 327-338.

Singh RB et al. Randomized, double-blind placebo-controlled trial of coenzyme Q10 in patients with acute myocardial infarction. 1998. Cardiovasc Drugs Ther 12: 347-353.

Singh RB et al. Effect of coenzyme Q10 on experimental atherosclerosis and chemical composition and quality of atheroma in rabbits. 2000. Atherosclerosis 148: 275-282.

Soja AM et al. Treatment of congestive heart failure with coenzyme Q10 illuminated by meta-analyses of clinical
trials. 1997. Molec Aspects Med. 18, Suppl: S159-S168.

Tresch DD. The clinical diagnosis of heart failure in older patients. 1997. J Am Geriatr Soc 45: 1128-1133.


Alleva R et al. The protective role of ubiquinol-10 against formation of lipid hydroperoxides in human seminal fluid. 1997. Molec Aspects Med 18, Suppl: S221-228.

Dlugosz A et al. The chemoprotective effect of coenzyme Q on lipids in the paint and lacquer industry workers. 1998. Intl J Occup Med Env Health 11: 153-163.

Ernster L et al. Biochemical, physiological and medical aspects of ubiquinone function. 1995. Biochim Biophys Acta 1271: 195-204.

Forsmark-Andree P et al. Evidence for a protective effect of endogenous ubiquinol against oxidative damage to mitochondrial protein and DNA during lipid peroxidation. 1994. Molec Aspects Med 15, Suppl: S73-S81.

Forsmark-Andree P et al. Lipid peroxidation and changes in the ubiquinone content and the respiratory chain enzymes of submitochondrial particles. 1997. Free Radic Biol Med 22: 391-400.

Halliwell B et al. Free radicals in biology and medicine, 3rd edn. Oxford, 1999.

Harman D. Aging: A theory based on free radical and radiation chemistry. 1956. J Gerontol 12: 298-300.

Harman D. The biological clock: the mitochondria? 1972.
J Am Geriatr Soc 20: 145-147.

Harman D. Extending functional life span. 1998. Exp Gerontol 33: 95-112.

Humphries KM et al. Inhibition of NADH-linked mitochondrial respiration by 4-hydroxy-2-nonenal. 1998. Biochemistry 37: 552-557.

Kontush A et al. Antioxidative activity of ubiquinol-10 at physiologic concentrations in human low density lipoprotein. 1995. Biochem Biophys Acta 1258: 177-187.

Lewin A et al. The effect of Coenzyme Q10 on sperm
motility and function. 1997. Molec Aspects Med 18, Suppl: S213-S219.

Miquel J et al. Mitochondrial role in cell aging. 1980. Exp Gerontol 15: 575-591.

Miquel J. An update on the oxygen stress-mitochondrial mutation theory of aging: genetic and evolutionary
implications. 1998. Exp Gerontol 33: 113-126.

Stocker R et al. Ubiquinol-10 protects human low density lipoprotein more efficiently against lipid peroxidation that does a-tocopherol. 1991. Proc Natl Acad Sci USA 88:
1646-1650.

Thomas S et al. Cosupplementation with coenzyme Q prevents the prooxidant effect of a-tocopherol and increases the resistance of LDL to transition metal-dependent
oxidation initiation. 1996. Arterioscler Thromb Vasc Biol 16:
687-696.

Thomas S et al. Inhibition of LDL oxidation by ubiquinol-10. A protective mechanism for coenzyme Q in atherolsclerosis? 1997. Molec Aspects Med 18, Suppl:
S85-S103.

Thomas S et al. Oxidation and antioxidation of human
low-density lipoprotein and plasma exposed to 3-morpholinosydnonimine and reagent peroxynitrite. 1998. Chem Res Toxicol 11: 484-494.



Byeeeeeeeeeeeeeeeee

Si, però non puoi dirci queste cose senza fornirci un pò di documentazione scientifica

[flexer77]

Originally posted by Guru
Si, però non puoi dirci queste cose senza fornirci un pò di documentazione scientifica