Il multivitaminici che fanno male?? Ma in che mondo vivevete? Sono essenziali le vitamine alla crescita muscolare. http://www.getbig.com/articles/faq-vit1.htm
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Mega-dosi di idrosolubili ci possono stare, nel senso che quantomeno non dovrebbero essere dannose, ma temo faccia ben poco andare molto sopra la RDA. Del resto nell'articolo lo dice, tutta la tiamina che gettate nel cesso dimostra che ne assorbite molto meno di quei 50 mg che generalmente stanno nelle pillole.Originariamente Scritto da wind636 Visualizza Messaggio
"There’s certainly no harm to taking this extra thiamin – but
no point to it, either. This is one case where the old skeptic’s
taunt is true: you really are flushing most of that extra
thiamin down the toilet! And the same is true of a lot of
the other B vitamins you’re taking. Doses should be based
on science – not nice, round numbers."
Last edited by Maverick87; 19-10-2012, 15:03:10.Commenta
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ma che cavolo oltre a questo articolo di studi seri fatti in doppio cieco o studi con le palle sotto perchè non li posti?
---------- Post added at 14:59:58 ---------- Previous post was at 14:54:15 ----------
ma che cavolo oltre a questo articolo di studi seri fatti in doppio cieco o studi con le palle sotto perchè non li posti?Commenta
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Queste sono tutte le ricerche citate nell'articolo. Entro stasera o domani dovrei riuscire a fare un riassunto dell'articolo
1 Miller ER 3rd, Pastor-Barriuso R, Dalal D, et al. Meta-analysis: high-dosage vitamin E
supplementation may increase all-cause mortality. Ann Intern Med. 2005 Jan 4;142(1):37-46.
2 Albanes D, Heinonen OP, Taylor PR, et al. Alpha-Tocopherol and beta-carotene supplements and
lung cancer incidence in the alpha-tocopherol, beta-carotene cancer prevention study: effects of baseline
characteristics and study compliance. J Natl Cancer Inst. 1996 Nov 6;88(21):1560-70.
3 Hennekens CH, Buring JE, Manson JE, et al. Lack of effect of long-term supplementation with beta
carotene on the incidence of malignant neoplasms and cardiovascular disease. N Engl J Med. 1996
May 2;334(18):1145-9.
4 Omenn GS, Goodman GE, Thornquist MD, et al. Effects of a combination of beta carotene and
vitamin A on lung cancer and cardiovascular disease. N Engl J Med. 1996 May 2;334(18):1150-5.
5 Brown BG, Zhao XQ, Chait A, et al. Simvastatin and niacin, antioxidant vitamins, or the combination
for the prevention of coronary disease. N Engl J Med. 2001 Nov 29;345(22):1583-92.
6 Waters DD, Alderman EL, Hsia J, et al. Effects of hormone replacement therapy and antioxidant
vitamin supplements on coronary atherosclerosis in postmenopausal women: a randomized controlled
trial. JAMA. 2002 Nov 20;288(19):2432-40.
7 Heart Protection Study Collaborative Group. MRC/BHF Heart Protection Study of antioxidant
vitamin supplementation in 20,536 high-risk individuals: a randomised placebo-controlled trial.
Lancet. 2002 Jul 6;360(9326):23-33.
8 Melhus H, Michaelsson K, Kindmark A, et al. Excessive dietary intake of vitamin A is associated with
reduced bone mineral density and increased risk for hip fracture. Ann Intern Med. 1998 Nov
15;129(10):770-8.
9 Feskanich D, Singh V, Willett WC, Colditz GA. Vitamin A intake and hip fractures among
postmenopausal women. JAMA. 2002 Jan 2;287(1):47-54.
10 Michaelsson K, Lithell H, Vessby B, Melhus H. Serum retinol levels and the risk of fracture. N Engl
J Med. 2003 Jan 23;348(4):287-94.
11 Opotowsky AR, Bilezikian JP. Serum vitamin A concentration and the risk of hip fracture among
women 50 to 74 years old in the United States: A prospective analysis of the NHANES I follow-up
study. Am J Med. 2004 Aug 1;117(3):169-74.
12 Promislow JH, Goodman-Gruen D, Slymen DJ, Barrett-Connor E. Retinol intake and bone mineral
density in the elderly: the Rancho Bernardo Study. J Bone Miner Res. 2002 Aug;17(8):1349-58.
13 Sowers MF, Wallace RB. Retinol, supplemental vitamin A and bone status. J Clin Epidemiol.
1990;43(7):693-9.
14 Freudenheim JL, Johnson NE, Smith EL. Relationships between usual nutrient intake and bonemineral
content of women 35-65 years of age: longitudinal and cross-sectional analysis. Am J Clin
Nutr. 1986 Dec;44(6):863-76.
15 Tang G, Qin J, Dolnikowski GG, Russell RM. Short-term (intestinal) and long-term (postintestinal)
conversion of beta-carotene to retinol in adults as assessed by a stable-isotope reference method. Am
J Clin Nutr. 2003 Aug;78(2):259-66.
16 Sandstead HH. Requirements and toxicity of essential trace elements, illustrated by zinc and
copper. Am J Clin Nutr. 1995 Mar;61(3 Suppl):621S-624S.
17 Klevay LM. Lack of a recommended dietary allowance for copper may be hazardous to your
health. J Am Coll Nutr. 1998 Aug;17(4):322-6.
18 Klevay LM, Moore RJ. Ischemic heart disease: toward a unified theory. In Lei KY, Carr TP (eds).
The Role of Copper in Lipid Metabolism. 1990; CRC Press, Boca Raton, FL:233-67
19 Thomas JA. Diet, micronutrients, and the prostate gland. Nutr Rev. 1999 Apr;57(4):95-103.
20 Leitzmann MF, Stampfer MJ, Wu K, et al. Zinc supplement use and risk of prostate cancer. J Natl
Cancer Inst. 2003 Jul 2;95(13):1004-7.
21 Greger JL. Dietary standards for manganese: overlap between nutritional and toxicological
studies. J Nutr. 1998 Feb;128(2 Suppl):368S-371S.
22 Kondakis XG, Makris N, Leotsinidis M, et al. Possible health effects of high manganese
concentration in drinking water. Arch Environ Health. 1989 May-Jun;44(3):175-8.
23 Vieregge P, Heinzow B, Korf G, et al. Long term exposure to manganese in rural well water has
no neurological effects. Can J Neurol Sci. 1995 Nov;22(4):286-9.
24 Powers KM, Smith-Weller T, Franklin GM, et al. Parkinson's disease risks associated with dietary
iron, manganese, and other nutrient intakes. Neurology. 2003 Jun 10;60(11):1761-6.
25 Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Vitamin A, Vitamin
K, Arsenic, Boron, Chromium, Copper, Iodine, Iron, Manganese, Molybdenum, Nickel, Silicon,
Vanadium, and Zinc. 2001; Washington, DC: National Academy Press.
26 Ministry of Agriculture, Fisheries and Food.1994 Total Diet Study: metals and other elements.
1997; Food Surveillance Information Sheet No. 131.
27 Van Poppel G,. Goldbohm RA. Epidemiologic evidence for beta-carotene and cancer prevention.
Am J Clin Nutr. 1995 Dec;62(6 Suppl):1393S-1402S.
28 Levin G, Mokady S. Antioxidant activity of 9-cis compared to all-trans beta-carotene in vitro. Free
Radic Biol Med. 1994 Jul;17(1):77-82.
29 Levin G, Yeshurun M, Mokady S. In vivo antiperoxidative effect of 9-cis beta-carotene compared
with that of the all-trans isomer. Nutr Cancer. 1997;27(3):293-7.
30 Ben-Amotz A, Levy Y. Bioavailability of a natural isomer mixture compared with synthetic all-trans
beta-carotene in human serum. Am J Clin Nutr. 1996 May;63(5):729-34.
31 Xue KX, Wu JZ, Ma GJ, et al. Comparative studies on genotoxicity and antigenotoxicity of
natural and synthetic beta-carotene stereoisomers. Mutat Res. 1998 Oct 12;418(2-3):73-8.
32 Iannuzzi A, Celentano E, Panico S, et al. Dietary and circulating antioxidant vitamins in relation
to carotid plaques in middle-aged women. Am J Clin Nutr. 2002 Sep;76(3):582-7.
33 Kushi LH, Folsom AR, Prineas RJ, et al. Dietary antioxidant vitamins and death from coronary heart
disease in postmenopausal women. N Engl J Med. 1996 May 2;334(18):1156-62.
34 Knekt P, Reunanen A, Jarvinen R, et al. Antioxidant vitamin intake and coronary mortality in a
longitudinal population study. Am J Epidemiol. 1994 Jun 15;139(12):1180-9.
35 Engelhart MJ, Geerlings MI, Ruitenberg A, et al. Dietary intake of antioxidants and risk of
Alzheimer disease. JAMA. 2002 Jun 26;287(24):3223-9.
36 Morris MC, Evans DA, Bienias JL, et al. Dietary intake of antioxidant nutrients and the risk of
incident Alzheimer disease in a biracial community study. JAMA. 2002 Jun 26;287(24):3230-7.
37 Masaki KH, Losonczy KG, Izmirlian G, et al. Association of vitamin E and C supplement use with
cognitive function and dementia in elderly men. Neurology. 2000 Mar 28;54(6):1265-72.
38 Brigelius-Flohe R, Traber MG. Vitamin E: function and metabolism. FASEB J. 1999
Jul;13(10):1145-55.
39 Lehmann J, Martin HL, Lashley EL, et al. Vitamin E in foods from high and low linoleic acid diets.
J Am Diet Assoc. 1986 Sep;86(9):1208-16.
40 Qureshi N, Qureshi AA. Tocotrienols: novel hypocholesterolemic agents with antioxidant
properties. In Packer L, Fuchs J (eds). Vitamin E in Health and Disease. 1993; New York: Marcel
Dekker, 247-67.
41 Heinonen M, Piironen V. The tocopherol, tocotrienol, and vitamin E content of the average Finnish
diet. Int J Vitam Nutr Res. 1991;61(1):27-32.
42 McLaughlin PJ,Weihrauch JL. Vitamin E content of foods. J Am Diet Assoc. 1979 Dec;75(6):647-65.
43 Bieri JG. Sources and consumption of antioxidants in the diet. JAOCS. 1984 Dec;61(12):1917-17.
44 Devaraj S, Traber MG. Gamma-tocopherol, the new vitamin E? Am J Clin Nutr. 2003
Mar;77(3):530-1.
45 Jiang Q, Christen S, Shigenaga MK, Ames BN. Gamma-tocopherol, the major form of vitamin E
in the US diet, deserves more attention. Am J Clin Nutr. 2001 Dec;74(6):714-22.
46 Nojiri S, Daida H, Mokuno H, et al. Association of serum antioxidant capacity with coronary artery
disease in middle-aged men. Jpn Heart J. 2001 Nov;42(6):677-90.
47 Kontush A, Spranger T, Reich A, et al. Lipophilic antioxidants in blood plasma as markers of
atherosclerosis: the role of alpha-carotene and gamma-tocopherol. Atherosclerosis. 1999
May;144(1):117-22.
48 Kristenson M, Zieden B, et al. Antioxidant state and mortality from coronary heart disease in
Lithuanian and Swedish men: concomitant cross sectional study of men aged 50. BMJ. 1997 Mar
1;314(7081):629-33.
49 Ohrvall M, Sundlof G, Vessby B. Gamma, but not alpha, tocopherol levels in serum are reduced
in coronary heart disease patients. J Intern Med. 1996 Feb;239(2):111-7.
50 Ruiz Rejon F, Martin-Pena G, Granado F, et al. Plasma status of retinol, alpha- and gammatocopherols,
and main carotenoids to first myocardial infarction: case control and follow-up study.
Nutrition. 2002 Jan;18(1):26-31.
51 Helzlsouer KJ, Huang HY, Alberg AJ, et al. Association between alpha-tocopherol, gammatocopherol,
selenium, and subsequent prostate cancer. J Natl Cancer Inst. 2000 Dec
20;92(24):2018-23.
52 Huang HY, Alberg AJ, Norkus EP, et al. Prospective study of antioxidant micronutrients in the blood
and the risk of developing prostate cancer. Am J Epidemiol. 2003 Feb 15;157(4):335-44.
53 Hensley K, Maidt ML, Yu Z, et al. Electrochemical analysis of protein nitrotyrosine and dityrosine
in the Alzheimer brain indicates region-specific accumulation. J Neurosci. 1998 Oct
15;18(20):8126-32.
54 Williamson KS, Gabbita SP, Mou S, et al. The nitration product 5-nitro-gamma-tocopherol is
increased in the Alzheimer brain. Nitric Oxide. 2002 Mar;6(2):221-7.
55 Olmedilla B, Granado F, Southon S, et al. A European multicentre, placebo-controlled
supplementation study with alpha-tocopherol, carotene-rich palm oil, lutein or lycopene: analysis of
serum responses. Clin Sci (Lond). 2002 Apr;102(4):447-56.
56 Baker H, Handelman GJ, Short S et al. Comparison of plasma alpha and gamma tocopherol levels
following chronic oral administration of either all-rac-alpha-tocopheryl acetate or RRR-alphatocopheryl
acetate in normal adult male subjects. Am J Clin Nutr. 1986 Mar;43(3):382-7.
57 Handelman GJ, Machlin LJ, Fitch K, et al. Oral alpha-tocopherol supplements decrease plasma
gamma-tocopherol levels in humans. J Nutr. 1985 Jun;115(6):807-13.
58 Handelman GJ, Epstein WL, Peerson J, et al. Human adipose alpha-tocopherol and gammatocopherol
kinetics during and after 1 y of alpha-tocopherol supplementation. Am J Clin Nutr. 1994
May;59(5):1025-32.
59 Dietrich M, Block G, Hudes M, et al. Antioxidant supplementation decreases lipid peroxidation
biomarker F(2)-isoprostanes in plasma of smokers. Cancer Epidemiol Biomarkers Prev. 2002
Jan;11(1):7-13.
60 Khor HT, Ng TT. Effects of administration of alpha-tocopherol and tocotrienols on serum lipids
and liver HMG CoA reductase activity. Int J Food Sci Nutr. 2000;51 Suppl:S3-11.
61 Qureshi AA, Pearce BC, Nor RM, et al. Dietary alpha-tocopherol attenuates the impact of
gamma-tocotrienol on hepatic 3-hydroxy-3-methylglutaryl coenzyme A reductase activity in chickens.
J Nutr. 1996 Feb;126(2):389-94.
62 Mensink RP, van Houwelingen AC, Kromhout D, Hornstra G. A vitamin E concentrate rich in
tocotrienols had no effect on serum lipids, lipoproteins, or platelet function in men with mildly elevated
serum lipid concentrations. Am J Clin Nutr. 1999 Feb;69(2):213-9.
63 Whanger PD. Selenocompounds in plants and animals and their biological significance. J Am Coll
Nutr. 2002 Jun;21(3):223-32.
64 Medina D, Thompson H, Ganther H, Ip C. Se-methylselenocysteine: a new compound for
chemoprevention of breast cancer. Nutr Cancer. 2001;40(1):12-7.
65 Ip C. Lessons from basic research in selenium and cancer prevention. J Nutr. 1998
Nov;128(11):1845-54.
66 Zittermann A. Effects of vitamin K on calcium and bone metabolism. Curr Opin Clin Nutr Metab
Care. 2001 Nov;4(6):483-7.
67 Allison AC. The possible role of vitamin K deficiency in the pathogenesis of Alzheimer's disease
and in augmenting brain damage associated with cardiovascular disease. Med Hypotheses. 2001
Aug;57(2):151-5.
68 Schurgers LJ, Dissel PE, Spronk HM, et al. Role of vitamin K and vitamin K-dependent proteins in
vascular calcification. Z Kardiol. 2001;90 Suppl 3:57-63.
69 Vermeer C. Prevention of arterial calcification by vitamin K2. In Miki T (ed). Vitamin K: A
Conference. Renewing Bone Metabolism. 2000; Tokyo: Intermedd Inc, 2-21.
70 Heaney RP. Meta-analysis of calcium bioavailability. Am J Therapeut. 2001 Jan/Feb;8(1):73.
71 Penland JG. Dietary boron, brain function, and cognitive performance. Environ Health Perspect.
1994 Nov;102 Suppl 7:65-72.
72 Newnham RE. Essentiality of boron for healthy bones and joints. Environ Health Perspect. 1994
Nov;102 Suppl 7:83-5.
73 Cui Y, Winton MI, Zhang ZF, et al. Dietary boron intake and prostate cancer risk. Oncol Rep.
2004 Apr;11(4):887-92.
74 Sutherland B, Strong P, King JC. Determining human dietary requirements for boron. Biol Trace
Elem Res. 1998 Winter;66(1-3):193-204.
75 Hunt CD, Friel JK, Johnson LK. Boron concentrations in milk from mothers of full-term and
premature infants. Am J Clin Nutr. 2004 Nov;80(5):1327-33.
76 Seaborn CD, Nielsen FH. Silicon deprivation decreases collagen formation in wounds and bone,
and ornithine transaminase enzyme activity in liver. Biol Trace Elem Res. 2002 Dec;89(3):251-61.
77 Seaborn CD, Nielsen FH. Silicon deprivation and arginine and cystine supplementation affect bone
collagen and bone and plasma trace mineral concentrations in rats. J Trace Elem Exp Med. 2002;
15(3):113-22.
78 Jugdaohsingh R, Tucker KL, Qiao N, et al. Dietary silicon intake is positively associated with bone
mineral density in men and premenopausal women of the Framingham Offspring cohort. J Bone Miner
Res. 2004 Feb;19(2):297-307.
79 Eisinger J, Clairet D. Effects of silicon, fluoride, etidronate and magnesium on bone mineral
density: a retrospective study. Magnes Res. 1993 Sep;6(3):247-9.
80 Mukherjee B, Patra B, Mahapatra S, et al. Vanadium--an element of atypical biological
significance. Toxicol Lett. 2004 Apr 21;150(2):135-43.
81 Schrauzer GN. Lithium: occurrence, dietary intakes, nutritional essentiality. J Am Coll Nutr. 2002
Feb;21(1):14-21.
82 Mai V, Colbert LH, Berrigan D, et al. Calorie restriction and diet composition modulate
spontaneous intestinal tumorigenesis in Apc(Min) mice through different mechanisms. Cancer Res.
2003 Apr 15;63(8):1752-5.
83 Duffy PH, Lewis SM, Mayhugh MA, et al. Effect of the AIN-93M purified diet and dietary
restriction on survival in Sprague-Dawley rats: implications for chronic studies. J Nutr. 2002
Jan;132(1):101-7.
84 Alink GM, Kuiper HA, Hollanders VM, Koeman JH. Effect of cooking and of vegetables and fruit
on 1,2-dimethylhydrazine-induced colon carcinogenesis in rats. In Waldron KW, Johnson IT, Fenwick
GR (eds). Food and Cancer Prevention: Chemical and Biological Aspects. 1993;Royal Society of
Chemistry, Cambridge:175-9.
85 Birt DF, Patil K, Pour PM. Comparative studies on the effects of semipurified and commercial diet
on longevity and spontaneous and induced lesions in the Syrian golden hamster. Nutr Cancer.
1985;7(3):167-77.
86 Newberne PM, Suphakarn V. Nutrition and cancer: a review, with emphasis on the role of vitamins
C and E and selenium. Nutr Cancer. 1983;5(2):107-19.
87 King JT, Visscher MB. Longevity as a function of diet in the C3H mouse. Fed Proc. 1950
Mar;9(1):70-1.
88 Shahidi F, Naczk M. Food phenolics: an overview. In Shahidi F, Naczk M (eds). Food phenolics:
sources, chemistry, effects, applications. 1995; Lancaster PA: Technomic Publishing Company Inc, 1-5.
89 World Cancer Research Fund, American Institute for Cancer Research. Food, Nutrition, and the
Prevention of Cancer: a Global Perspective. 1997; Washington, DC: American Institute for Cancer
Research.
90 Rafter JJ. Scientific basis of biomarkers and benefits of functional foods for reduction of disease
risk: cancer. Br J Nutr. 2002 Nov;88 Suppl 2:S219-24.
91 Van Duyn MA, Pivonka E. Overview of the health benefits of fruit and vegetable consumption for
the dietetics professional: selected literature. J Am Diet Assoc. 2000 Dec;100(12):1511-21.
92 Giovannucci E. Tomatoes, tomato-based products, lycopene, and cancer: review of the
epidemiologic literature. J Natl Cancer Inst. 1999 Feb 17;91(4):317-31.
93 Clydesdale FM. ILSI North America Food Component Reports. Food Science And Nutrition. Crit
Rev Food Sci Nutr. 1999;39(3).
94 Steinmetz KA, Potter JD. Vegetables, fruit, and cancer prevention: a review. J Am Diet Assoc.
1996 Oct;96(10):1027-39.
95 Bradlow HL, Telang NT, Sepkovic DW, Osborne MP. Phytochemicals as modulators of cancer risk.
Adv Exp Med Biol. 1999;472:207-21.
96 Potter JD, Steinmetz K. Vegetables, fruit and phytoestrogens as preventive agents. IARC Sci Publ.
1996;(139):61-90.
97 Matusheski NV, Jeffery EH. Processing conditions improve the yield of the anticarcinogen
sulforaphane from broccoli. 2002 Mtg, Inst Food Technol. 2002; Abs100C-25.
98 Conaway CC, Getahun SM, Liebes LL, Pusateri DJ, Topham DK, Botero-Omary M, Chung FL.
Disposition of glucosinolates and sulforaphane in humans after ingestion of steamed and fresh
broccoli. Nutr Cancer. 2000;38(2):168-78.
99 Chen L, Stacewicz-Sapuntzakis M, Duncan C, Sharifi R, Ghosh L, van Breemen R, Ashton D, Bowen
PE. Oxidative DNA damage in prostate cancer patients consuming tomato sauce-based entrees as a
whole-food intervention. J Natl Cancer Inst. 2001 Dec 19;93(24):1872-9.
100 Kucuk O, Sarkar FH, Sakr W, et al. Phase II randomized clinical trial of lycopene
supplementation before radical prostatectomy. Cancer Epidemiol Biomarkers Prev. 2001
Aug;10(8):861-8.
101 Bell MC, Crowley-Nowick P, Bradlow HL, Sepkovic DW, Schmidt-Grimminger D, Howell P,
Mayeaux EJ, Tucker A, Turbat-Herrera EA, Mathis JM. Placebo-controlled trial of indole-3-carbinol
in the treatment of CIN. Gynecol Oncol. 2000 Aug;78(2):123-9.
102 Scalbert A, Morand C, Manach C, Remesy C. Absorption and metabolism of polyphenols in the
gut and impact on health. Biomed Pharmacother. 2002 Aug;56(6):276-82.
103 Rechner AR, Kuhnle G, Bremner P, Hubbard GP, Moore KP, Rice-Evans CA. The metabolic fate of
dietary polyphenols in humans. Free Radic Biol Med. 2002 Jul 15;33(2):220-35.
104 Scalbert A, Williamson G. Dietary intake and bioavailability of polyphenols. J Nutr. 2000
Aug;130(8S Suppl):2073S-85S.
105 Ullmann U, Haller J, Decourt JP, Girault N, Girault J, Richard-Caudron AS, Pineau B, Weber P. A
single ascending dose study of epigallocatechin gallate in healthy volunteers. J Int Med Res. 2003
Mar-Apr;31(2):88-101.
106 Lee MJ, Maliakal P, Chen L, Meng X, Bondoc FY, Prabhu S, Lambert G, Mohr S, Yang CS.
Pharmacokinetics of tea catechins after ingestion of green tea and (-)-epigallocatechin-3-gallate by
humans: formation of different metabolites and individual variability. Cancer Epidemiol Biomarkers
Prev. 2002 Oct;11(10 Pt 1):1025-32.
107 Meng X, Sang S, Zhu N, Lu H, Sheng S, Lee MJ, Ho CT, Yang CS. Identification and
characterization of methylated and ring-fission metabolites of tea catechins formed in humans, mice,
and rats. Chem Res Toxicol. 2002 Aug;15(8):1042-50.
108 Van Amelsvoort JM, Van Hof KH, Mathot JN, Mulder TP, Wiersma A, Tijburg LB. Plasma
concentrations of individual tea catechins after a single oral dose in humans. Xenobiotica. 2001
Dec;31(12):891-901.
109 Li C, Meng X, Winnik B, Lee MJ, Lu H, Sheng S, Buckley B, Yang CS. Analysis of urinary
metabolites of tea catechins by liquid chromatography/electrospray ionization mass spectrometry.
Chem Res Toxicol. 2001 Jun;14(6):702-7.
110 Chow HH, Cai Y, Alberts DS, Hakim I, Dorr R, Shahi F, Crowell JA, Yang CS, Hara Y. Phase I
pharmacokinetic study of tea polyphenols following single-dose administration of epigallocatechin
gallate and polyphenon E. Cancer Epidemiol Biomarkers Prev. 2001 Jan;10(1):53-8.
111 Miyazawa T. Absorption, metabolism and antioxidative effects of tea catechin in humans.
Biofactors. 2000;13(1-4):55-9.
112 van het Hof KH, Wiseman SA, Yang CS, Tijburg LB. Plasma and lipoprotein levels of tea
catechins following repeated tea consumption. Proc Soc Exp Biol Med. 1999 Apr;220(4):203-9.
113 Zhang G, Miura Y, Yagasaki K. Induction of apoptosis and cell cycle arrest in cancer cells by in vivo
metabolites of teas. Nutr Cancer. 2000;38(2):265-73.
114 Nakachi K, Eguchi H, Imai K. Can teatime increase one's lifetime? Ageing Res Rev. 2003
Jan;2(1):1-10.
115 Wu AH, Yu MC, Tseng CC, Hankin J, Pike MC. Green tea and risk of breast cancer in Asian
Americans. Int J Cancer. 2003 Sep 10;106(4):574-9.
116 Nakachi K, Eguchi H, Imai K. Effects of drinking green tea on cancer risk and physiology of
cigarette smokers, observed in a prospective cohort study among a Japanese general population. Proc
AACR Annu Meetg. 2002; Abs2353.
117 Bushman JL. Green tea and cancer in humans: a review of the literature. Nutr Cancer.
1998;31(3):151-9.
118 Nakachi K, Matsuyama S, Miyake S, Suganuma M, Imai K. Preventive effects of drinking green
tea on cancer and cardiovascular disease: epidemiological evidence for multiple targeting prevention.
Biofactors. 2000;13(1-4):49-54.
119 Hirano R, Momiyama Y, Takahashi R, Taniguchi H, Kondo K, Nakamura H, Ohsuzu F.
Comparison of green tea intake in Japanese patients with and without angiographic coronary artery
disease. Am J Cardiol. 2002 Nov 15;90(10):1150-3.
120 Nielsen SE, Young JF, Daneshvar B, Lauridsen ST, Knuthsen P, Sandstrom B, Dragsted LO. Effect
of parsley (Petroselinum crispum) intake on urinary apigenin excretion, blood antioxidant enzymes
and biomarkers for oxidative stress in human subjects. Br J Nutr. 1999 Jun;81(6):447-55.
121 Shimoi K, Okada H, Furugori M, Goda T, Takase S, Suzuki M, Hara Y, Yamamoto H, Kinae N.
Intestinal absorption of luteolin and luteolin 7-O-beta-glucoside in rats and humans. FEBS Lett. 1998
Nov 6;438(3):220-4.
122 Felgines C, Talavera S, Gonthier MP, Texier O, Scalbert A, Lamaison JL, Remesy C. Strawberry
anthocyanins are recovered in urine as glucuro- and sulfoconjugates in humans. J Nutr. 2003
May;133(5):1296-301.
123 Ross JA, Kasum CM. Dietary flavonoids: bioavailability, metabolic effects, and safety. Annu Rev
Nutr. 2002;22:19-34.
124 Saller R, Meier R, Brignoli R. The use of silymarin in the treatment of liver diseases. Drugs.
2001;61(14):2035-63.
125 Wellington K, Jarvis B. Silymarin: a review of its clinical properties in the management of hepatic
disorders. BioDrugs. 2001;15(7):465-89.
126 Wargovich MJ. Nutrition and cancer: the herbal revolution. Curr Opin Clin Nutr Metab Care.
1999 Sep;2(5):421-4.
127 Slattery ML, Benson J, Curtin K, Ma KN, Schaeffer D, Potter JD. Carotenoids and colon cancer.
Am J Clin Nutr. 2000 Feb;71(2):575-82.
128 Rohan TE, Jain M, Howe GR, Miller AB. A cohort study of dietary carotenoids and lung cancer
risk in women (Canada). Cancer Causes Control. 2002 Apr;13(3):231-7.
129 Giovannucci E, Rimm EB, Liu Y, Stampfer MJ, Willett WC. A prospective study of tomato
products, lycopene, and prostate cancer risk. J Natl Cancer Inst. 2002 Mar 6;94(5):391-8.
130 Michaud DS, Feskanich D, Rimm EB, Colditz GA, Speizer FE, Willett WC, Giovannucci E. Intake
of specific carotenoids and risk of lung cancer in 2 prospective US cohorts. Am J Clin Nutr. 2000
Oct;72(4):990-7.
131 Terry P, Jain M, Miller AB, Howe GR, Rohan TE. Dietary carotenoids and risk of breast cancer.
Am J Clin Nutr. 2002 Oct;76(4):883-8.
132 Giovannucci E, Ascherio A, Rimm EB, Stampfer MJ, Colditz GA, Willett WC. Intake of
carotenoids and retinol in relation to risk of prostate cancer. J Natl Cancer Inst. 1995 Dec
6;87(23):1767-76.
133 Ziegler RG, Colavito EA, Hartge P, McAdams MJ, Schoenberg JB, Mason TJ, Fraumeni JF Jr.
Importance of alpha-carotene, beta-carotene, and other phytochemicals in the etiology of lung
cancer. J Natl Cancer Inst. 1996 May 1;88(9):612-5.
134 Neuhouser ML, Patterson RE, Thornquist MD, Omenn GS, King IB, Goodman GE. Fruits and
Vegetables Are Associated with Lower Lung Cancer Risk Only in the Placebo Arm of the beta-
Carotene and Retinol Efficacy Trial (CARET). Cancer Epidemiol Biomarkers Prev. 2003
Apr;12(4):350-8.
135 Dr. Dominique Michaud (personal communication).
136 West CE, Eilander A, van Lieshout M. Consequences of revised estimates of carotenoid
bioefficacy for dietary control of vitamin A deficiency in developing countries. J Nutr. 2002
Sep;132(9 Suppl):2920S-2926S.
137 Liu C, Russell RM, Wang XD. Exposing ferrets to cigarette smoke and a pharmacological dose
of beta-carotene supplementation enhance in vitro retinoic acid catabolism in lungs via induction of
cytochrome P450 enzymes. J Nutr. 2003 Jan;133(1):173-9.
138 Paolini M, Antelli A, Pozzetti L, Spetlova D, Perocco P, Valgimigli L, Pedulli GF, Cantelli-Forti G.
Induction of cytochrome P450 enzymes and over-generation of oxygen radicals in beta-carotene
supplemented rats. Carcinogenesis. 2001 Sep;22(9):1483-95.
139 Liu C, Wang XD, Bronson RT, Smith DE, Krinsky NI, Russell RM. Effects of physiological versus
pharmacological beta-carotene supplementation on cell proliferation and histopathological changes
in the lungs of cigarette smoke-exposed ferrets. Carcinogenesis. 2000 Dec;21(12):2245-53.
140 Hercberg S, Galan P, Preziosi P, et al. The SU.VI.MAX Study: A Randomized, Placebo-Controlled
Trial of the Health Effects of Antioxidant Vitamins and Minerals. Arch Intern Med. 2004 Nov
22;164(21):2335-2342.
141 Kodentsova VM, Vrzhesinskaia OA, Sokol'nikov AA, et al. The effect of riboflavin supply on
metabolism of water-soluble vitamins. Vopr Med Khim. 1993 Sep-Oct;39(5):29-33.
142 Ballmer PE. Vitamins and metals: possible hazards for humans. Schweiz Med Wochenschr. 1996
Apr 13;126(15):607-11.
143 Heinrich HC. Thiamin- und folsäuremangel bei chronischem alkoholismus, eisen- und
cobalaminmangel bei veganischer ernährung. Ernährungs-Umschau. 1990;37:594-607.
144 Thomson AD, Leevy CM. Observations on the mechanism of thiamin hydrochloride absorption in
man. Clin Sci. 1972 Aug;43(2):153-63.
145 Morrison AB, Campbell JA. Vitamin absorption studies I. Factors influencing the excretion of oral
test doses of thiamine and riboflavin by human subjects. J Nutr. 1960 Dec;72(4):435-40.
146 Friedemann TE, Kumeciak TC, Keegan PK, Sheft BB. The absorption, destruction, and excretion
of orally adminstered thiamine by human subjects. Gastroenterol. 1948 Jul;11(1):100-14.
147 Davis RE, Icke GC. Clinical chemistry of thiamin. Adv Clin Chem. 1983;23:93-140.
148 Tanphaichitr V. Thiamin. In Shils ME, Olson JA, Shike M, Ross AC. Modern Nutrition in Health
and Disease. Ninth Edition. 1999; New York: Lippincott Wiliams & Wilkins,381-9.
149 Loew D. Pharmacokinetics of thiamine derivatives especially of benfotiamine. Int J Clin
Pharmacol Ther. 1996 Feb;34(2):47-50.
150 Fox CH, Eberl M. Phytic acid (IP6), novel broad spectrum anti-neoplastic agent: a systematic
review. Complement Ther Med. 2002 Dec;10(4):229-34.
151 Berlyne GM, Ben-Ari J, Nord E, Shainkin R. Bedouin osteomalacia due to calcium deprivation
caused by high phytic acid content of unleavened bread. Am J Clin Nutr. 1973 Sep;26(9):910-1.
152 Ford JA, Colhoun EM, McIntosh WB, Dunnigan MG. Biochemical response of late rickets and
osteomalacia to a chupatty-free diet. Br Med J. 1972 Aug 19;3(824):446-7.
153 Stephens WP, Klimiuk PS, Berry JL, Mawer EB. Annual high-dose vitamin D prophylaxis in Asian
immigrants. Lancet. 1981 Nov 28;2(8257):1199-202.
154 Vucenik I, Yang GY, Shamsuddin AM. Comparison of pure inositol hexaphosphate and high-bran
diet in the prevention of DMBA-induced rat mammary carcinogenesis. Nutr Cancer. 1997;28(1):7-13.
155 Samman S, Sandstrom B, Toft MB, et al. Green tea or rosemary extract added to foods reduces
nonheme-iron absorption. Am J Clin Nutr. 2001 Mar;73(3):607-12.
156 Keskin Y, Moschonis G, Dimitriou M, et al. Prevalence of iron deficiency among schoolchildren
of different socio-economic status in urban Turkey. Eur J Clin Nutr. (In Press).
157 Hashizume M, Shimoda T, Sasaki S, et al. Anaemia in relation to low bioavailability of dietary
iron among school-aged children in the Aral Sea region, Kazakhstan. Int J Food Sci Nutr. 2004
Feb;55(1):37-43.
158 Grant CC, Wall CR, Wilson C, Taua N. Risk factors for iron deficiency in a hospitalized urban
New Zealand population. J Paediatr Child Health. 2003 Mar;39(2):100-6.
159 Gopaldas T, Gujral S. Empowering a tea-plantation community to improve its micronutrient
health. Food Nutr Bull. 2002 Jun;23(2):143-52.
160 Chang MC, Bailey JW, Collins JL. Dietary tannins from cowpeas and tea transiently alter
apparent calcium absorption but not absorption and utilization of protein in rats. J Nutr. 1994
Feb;124(2):283-8
161 Zeyuan D, Bingying T, Xiaolin L et al. Effect of green tea and black tea on the metabolisms of
mineral elements in old rats. Biol Trace Elem Res. 1998 Oct;65(1):75-86
162 Ganji V, Kies CV. Zinc bioavailability and tea consumption. Studies in healthy humans consuming
self-selected and laboratory-controlled diets. Plant Foods Hum Nutr. 1994 Oct;46(3):267-76.
163 Nakano M, Kawanishi Y, Kamohara S, et al. Oxidative DNA damage (8-
hydroxydeoxyguanosine) and body iron status: a study on 2507 healthy people. Free Radic Biol Med.
2003 Oct 1;35(7):826-32.
164 Ritchie CW, Bush AI, Mackinnon A, et al. Metal-protein attenuation with iodochlorhydroxyquin
(clioquinol) targeting Abeta amyloid deposition and toxicity in Alzheimer disease: a pilot phase 2
clinical trial. Arch Neurol. 2003 Dec;60(12):1685-91.
165 Ren Y, Tian H, Li X, Liang J, Zhao G. Elevated serum ferritin concentrations in a glucose-impaired
population and in normal glucose tolerant first-degree relatives in familial type 2 diabetic pedigrees.
Diabetes Care. 2004 Feb;27(2):622-3.
166 Jiang R, Manson JE, Meigs JB, et al. Body iron stores in relation to risk of type 2 diabetes in
apparently healthy women. JAMA. 2004 Feb 11;291(6):711-7.
167 Ford ES, Cogswell ME. Diabetes and serum ferritin concentration among U.S. adults. Diabetes
Care. 1999 Dec;22(12):1978-83.
168 de Valk B, Marx JJ. Iron, atherosclerosis, and ischemic heart disease. Arch Intern Med. 1999 Jul
26;159(14):1542-8.Commenta
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R: Alla larga dai multi ad alto dosaggio
perchè ti ostini a postare studi dove si parla solo di dosi da cavallo?ripeto di postarmi uno studio su un atleta ammalatosi!
ps: mio nonno attaccato all ossigeno,il dottore gli ha prescritto forti multivitaminici!
corro a dirgli che sta per morire
Inviato dal mio GT-I9300 con Tapatalk 2Commenta
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Ma quali dosi da cavallo? L'articolo mette in discussione proprio i multivitaminici e i dosaggi standard di questi integratori.Originariamente Scritto da torcia87 Visualizza MessaggioCommenta
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ma se io non faccio niente dalla mattina alla sera e mi ingozzo di dolci ad esempio cosa mi accade?
problemi cardiovascolari, colesterolo alto, rischio di diabete obesità e quant'altro.
Bisogna guardare le cose da un punto di vista critico!Commenta
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R: Alla larga dai multi ad alto dosaggio
addirittura noto uno studio sul cardo mariano che è pericoloso?
Inviato dal mio GT-I9300 con Tapatalk 2Commenta
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E poi basta con questa storia degli atleti di qui, atleti di là! Ma pensate che alzare i pesi e tirare su un po' di muscoli vi trasformi in degli xmen superdotati??Commenta
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dimmi oltre a leggere qualcosa quà e là hai qualche competenza medica?Commenta
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da questa risposta si evince la tua ignoranza sulla differenza da uno che si allena a uno che il maggior sforzo giornaliero è quello di aprire il barattolo della nutellaOriginariamente Scritto da Maverick87 Visualizza Messaggio
atleta:3000kcal giornaliere con 450 cho ecc ecc...BENESSERE
nullafacente vagabondo:3000kcal giornaliere con 450 cho ecc ecc...OBESO
è un esempio stupido per farti capire l'assimiliazione dei macro nutrienti per uno sportivo e uno no!la stessa cosa vale per le vitamine!
addirittura si parla di silimarina pericolosa ecc...fai un appello mondiale a chi prende molecole 17a-metilate(il primo esempio venuto in mente)di non usare più epa-protettori!!Commenta
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Non possiedo competenze mediche e del resto non mi sono inventato nulla, mi sono informato e ho cambiato idea sull'integrazione vitaminica, prima la pensavo esattamente come voi, che più fosse meglio, ma proprio perché ero poco e male informato.Originariamente Scritto da gianlu9292 Visualizza MessaggioLast edited by Maverick87; 19-10-2012, 16:44:48.Commenta
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ottimo vedi ? puo' anche essere che venga espulsa una buona parte ma tu stavi dicendo altro ... sostieni che alte dosi provochino malattie mortali non che siano solo soldi buttati ... ed è ben diverso !Originariamente Scritto da Maverick87 Visualizza Messaggio
Poi per carità anche l'alcool è potenzialmente mortale ... quindi che facciamo lo aboliamo ?
la carne rossa favorisce l'insorgere del cancro del colon quindi che facciamo aboliamo la carne rossa ?Commenta
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e perchè non ci pensi bene?ora che hai letto questo la pensi così e se magari tra un mese nè leggi un altro che dice il contrario che fai torni a reintegrarli?Originariamente Scritto da Maverick87 Visualizza Messaggio
informati a tutto tondo.Commenta
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