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1: J Appl Physiol. 1999 Aug;87(2):598-604.
Role of submaximal exercise in promoting creatine and glycogen accumulation in
human skeletal muscle.
Robinson TM, Sewell DA, Hultman E, Greenhaff PL.
School of Biomedical Sciences, University of Nottingham Medical School, Queen's
Medical Centre, Nottingham NG7 2UH, United Kingdom.
We examined the effect of glycogen-depleting exercise on subsequent muscle total
creatine (TCr) accumulation and glycogen resynthesis during postexercise periods
when the diet was supplemented with carbohydrate (CHO) or creatine (Cr) + CHO.
Fourteen subjects performed one-legged cycling exercise to exhaustion. Muscle
biopsies were taken from the exhausted (Ex) and nonexhausted (Nex) limbs after
exercise and after 6 h and 5 days of recovery, during which CHO (CHO group, n =
7) or Cr + CHO (Cr+CHO group, n = 7) supplements were ingested. Muscle TCr
concentration ([TCr]) was unchanged in both groups 6 h after supplementation
commenced but had increased in the Ex (P < 0.001) and Nex limbs (P < 0.05) of the
Cr+CHO group after 5 days. Greater TCr accumulation was achieved in the Ex limbs
(P < 0.01) of this group. Glycogen was increased above nonexercised
concentrations in the Ex limbs of both groups after 5 days, with the
concentration being greater in the Cr+CHO group (P = 0.06). Thus a single bout of
exercise enhanced muscle Cr accumulation, and this effect was restricted to the
exercised muscle. However, exercise also diminished CHO-mediated insulin release,
which may have attenuated insulin-mediated muscle Cr accumulation. Ingesting Cr
with CHO also augmented glycogen supercompensation in the exercised muscle.
Publication Types:
Clinical Trial
Research Support, Non-U.S. Gov't
PMID: 10444618 [PubMed - indexed for MEDLINE]
Scusate se è un pò lungo ma...
E mi scuso se ci ho messo un pò...
mao
Io cerco sempre le condizioni ottimali...
1: J Appl Physiol. 1999 Aug;87(2):598-604.
Role of submaximal exercise in promoting creatine and glycogen accumulation in
human skeletal muscle.
Robinson TM, Sewell DA, Hultman E, Greenhaff PL.
School of Biomedical Sciences, University of Nottingham Medical School, Queen's
Medical Centre, Nottingham NG7 2UH, United Kingdom.
We examined the effect of glycogen-depleting exercise on subsequent muscle total
creatine (TCr) accumulation and glycogen resynthesis during postexercise periods
when the diet was supplemented with carbohydrate (CHO) or creatine (Cr) + CHO.
Fourteen subjects performed one-legged cycling exercise to exhaustion. Muscle
biopsies were taken from the exhausted (Ex) and nonexhausted (Nex) limbs after
exercise and after 6 h and 5 days of recovery, during which CHO (CHO group, n =
7) or Cr + CHO (Cr+CHO group, n = 7) supplements were ingested. Muscle TCr
concentration ([TCr]) was unchanged in both groups 6 h after supplementation
commenced but had increased in the Ex (P < 0.001) and Nex limbs (P < 0.05) of the
Cr+CHO group after 5 days. Greater TCr accumulation was achieved in the Ex limbs
(P < 0.01) of this group. Glycogen was increased above nonexercised
concentrations in the Ex limbs of both groups after 5 days, with the
concentration being greater in the Cr+CHO group (P = 0.06). Thus a single bout of
exercise enhanced muscle Cr accumulation, and this effect was restricted to the
exercised muscle. However, exercise also diminished CHO-mediated insulin release,
which may have attenuated insulin-mediated muscle Cr accumulation. Ingesting Cr
with CHO also augmented glycogen supercompensation in the exercised muscle.
Publication Types:
Clinical Trial
Research Support, Non-U.S. Gov't
PMID: 10444618 [PubMed - indexed for MEDLINE]
Scusate se è un pò lungo ma...
E mi scuso se ci ho messo un pò...
mao
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